CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE PEPTIDE SUBSTRATE TKCVFM AND AN ANALOG OF FARNESYL DIPHOSPHATE

CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE PEPTIDE SUBSTRATE TKCVFM AND AN ANALOG OF FARNESYL DIPHOSPHATE Descriptor: ACETIC ACID, PROTEIN FARNESYLTRANSFERASE, ALPHA SUBUNIT, ... Authors: Long, S.B, Casey, P.J, Beese, L.S. Deposit date: 2001-06-11 Release date: 2001-11-02 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics. Proc.Natl.Acad.Sci.USA, 98, 2001与肽底物TKCVFM及法尼基二磷酸（farnesyl diphosphate）类似物结合的大鼠蛋白法尼基转移酶（protein farnesyltransferase）晶体结构 描述项：乙酸、蛋白法尼基转移酶（protein farnesyltransferase）、α亚基…… 作者：Long S.B、Casey P.J、Beese L.S. 提交日期：2001-06-11 发布日期：2001-11-02 最后修改日期：2023-08-16 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.2 Å 引用文献：人源蛋白法尼基转移酶晶体结构揭示CaaX四肽及其模拟物的抑制机制。《美国国家科学院院刊（Proc.Natl.Acad.Sci.USA）》，第98卷，2001年