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Transcriptome-wide analysis of mRNA decay in normal and osteoarthritic human articular chondrocytes

ChEBI2014-12-03 更新2026-07-21 收录

RNA稳定性调控

关节炎分子机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-2723 数据链接链接失效反馈

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资源简介：

Transcriptome-wide analysis of mRNA decay in normal and osteoarthritic human articular chondrocytes

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创建时间：

2014-12-03

关节炎分子机制

转录组生物标志物

Meniscus plays an important role in joint homeostasis. Tear or degeneration of meniscus might facilitate the process of knee osteoarthritis (OA). Hence, to investigate the transcriptome change during

NIAID Data Ecosystem90

Additional file 2: of Widespread changes in mRNA stability contribute to quiescence-specific gene expression patterns in a fibroblast model of quiescence

RNA稳定性调控

细胞静息基因表达

Gene ontology tables of genes with fast or slow decaying genes in both proliferating and quiescent fibroblasts. (XLSX 69Â kb)

NIAID Data Ecosystem40

A Click Chemistry-Based Biorthogonal Approach for the Detection and Identification of Protein Lysine Malonylation for Osteoarthritis Research

蛋白质翻译后修饰

关节炎分子机制

Lysine malonylation is a post-translational modification in which a malonyl group, characterized by a negatively charged carboxylate, is covalently attached to the ε-amino side chain of lysine, influe

NIAID Data Ecosystem00

RNA sequencing of subchondral bone from patients that underwent a joint replacement surgery due to osteoarthritis.

关节炎分子机制

软骨基因表达

Osteoarthritis (OA) has a considerable genetic component. Genetic research has resulted in many insights into underlying disease pathways. Nonetheless, follow up studies of identified susceptibility g

NIAID Data Ecosystem40

WNK2 regulates the response to hyperosmotic stress in chondrocytes

高渗应激信号传导

关节炎分子机制

How chondrocytes of the synovial joint sense and respond to hyperosmotic stress to maintain joint homeostasis over time is undetermined. The With-No-Lysine (K) (WNK) protein kinases are major intracel

NIAID Data Ecosystem20

Transcriptome-wide analysis of mRNA decay in normal and osteoarthritic human articular chondrocytes

资源简介：

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