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Combination effect of G-TPP and LXR623 on stem cell like glioma cells

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE104272
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We performed microarray analysis in order to evaluate the combination effect of the mitochondrial matrix chaperone inhibitor gamitrinib-triphenylphosphonium (G-TPP) and Liver X receptor agonist LXR623 on gene expression in stem cell like glioma cells (NCH644). NCH644 cells were treated with 1 µM of G-TPP, 5 µM of LXR623, both treatments, or neither treatment, in 0.1% DMSO. After 24 hours treatment, total RNA was isolated and analyzed.
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2021-07-25
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