Multiomics Point of Departure (moPOD) Modeling Supports an Adverse Outcome Pathway Network for Ionizing Radiation

This study aims to investigate dose-dependent transcriptomic responses of Daphnia magna after chronic exposure to gamma radiation. RNA sequecing was performed after 4 days and 8 days exposure. Differentially expressed genes and major pathways enriched were characerized to provide insights into the chronic effects of gamma radiation. Overall design: Neonatal Daphnia magna were exposed to 0.4-100 mGy/h gamma radiation for