Catalyst Deactivation of a Monoligated CyJohnPhos-Bound Nickel(0) Complex
收藏NIAID Data Ecosystem2026-05-01 收录
下载链接：
https://figshare.com/articles/dataset/Catalyst_Deactivation_of_a_Monoligated_CyJohnPhos-Bound_Nickel_0_Complex/24802529
下载链接
链接失效反馈官方服务：
资源简介：
Cross-coupling catalysts are prone
to unproductive side
reactivity,
which can limit their practical use in synthetic chemistry. A detailed
understanding of these pathways and the conditions that enable them
is important for reaction optimization and rational catalyst design.
In this work, we report the off-cycle reactivity of a monoligated,
(2-biphenyl)dicyclohexylphosphine (CyJohnPhos)-bound Ni0 complex following product-forming reductive elimination. In the
absence of substrate, free phosphine ligand, or π-accepting
additives, dimerization of (CyJohnPhos)Ni0 occurs, followed
by C–P bond activation of the ligand to form a phosphido-bridged
Ni0/NiII dimer; both the Ni0/Ni0 and Ni0/NiII dimers were structurally
characterized. Monomeric (CyJohnPhos)Ni0 must be intercepted
by the substrate or free ligand to prevent irreversible dimerization
and catalyst deactivation.
创建时间：
2023-12-13
