Black tea alleviates particulate matter-induced lung injury via the gut-lung axis in mice

Exposure to particulate matters (PMs) induces lung injury and gut microbiota disruption in mice. While daily intake of black tea or its fractions, including ethanol-soluble fraction (ES) and ethanol precipitate fraction (EP), can provide pre-protection against the PM-induced lung injury. Furthermore, the gut microbiota differentially reshaped by tea infusion (TI) and its fractions directly alleviate the injury induced by PMs, indicating gut microbiota mediates the protective effects of black tea and its fractions. Here, we performed gut microbiota 16sRNA sequencing on mice from each treatment groups.