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Absence of the eisosome causes general transcriptome remodeling of the yeast cell

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We investigated the effect of the absence of the eisosome on the overall yeast transcriptome by gene expression profiling analysis. We used data obtained from RNA-seq (polyA enrichment of total RNA isolates) of 3 different strains, specifically wild type (BY4742), a strain missing PIL1 gene that forms eisosome remanants instead of eisosome and our newly described seg1Δnce102Δpil1Δ strain, which forms neither eisosomes, nor eisosome remnants, even in the response to stress.

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