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GGTase-Iβ deletion in Intestinal Epithelial Cells

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE72781
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Prenylation is a post-translational modification of proteins consisting on the attachment of a lipid residue (isoprenoid). GGTase-I is one of the prenyltransferases catalyzing prenylation. Using mice with an inducible intestinal epihtelial cell specific deletion of GGTase-Iβ we analyzed the impact of geranylgeranylation within intestinal epithelium. Intestinal epithelial cells were isolated from 3 control mice and 3 mice with a codnitional deletion of GGTase-Iβ in Intestinal Epithelial Cells. RNA was isolated and subjected to Affymetrix gene chip analysis
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2019-02-11
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