<b>Pulmonary Microbiota and Lung Cancer</b>
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This study systematically analyzes the research landscape of lung cancer and pulmonary microbiota from 2015 to 2024 using bibliometric methods. Data from the Web of Science Core Collection were examined to identify key contributors, research hotspots, and evolving trends.<b> </b>Results revealed a significant shift in focus from infections and inflammation to immunotherapy and microbial biomarkers, reflecting a growing emphasis on clinical translation. Major contributors, including China and the United States, along with leading journals, have driven progress in this interdisciplinary field, highlighting the role of microbial dysbiosis in tumor development and immune modulation.The findings underscore the potential of pulmonary microbiota as diagnostic tools and therapeutic targets, particularly in enhancing immunotherapy outcomes. This study provides a comprehensive overview of the field, offering valuable insights into its current status and future directions, and lays a foundation for further exploration in personalized medicine and multidisciplinary collaborations.
本研究采用文献计量学方法(bibliometric methods),系统分析了2015年至2024年间肺癌与肺部微生物群(pulmonary microbiota)的研究态势。本研究对Web of Science核心合集(Web of Science Core Collection)中的数据进行分析,以识别该领域的核心贡献主体、研究热点及演化趋势。研究结果表明,该领域的研究焦点已从感染与炎症显著转向免疫治疗与微生物生物标志物,反映出学界对临床转化的重视程度与日俱增。包括中国、美国在内的核心贡献方,以及顶尖学术期刊共同推动了这一交叉领域的发展,凸显了微生物群失调在肿瘤发生与免疫调控中的关键作用。本研究结果同时强调,肺部微生物群具备作为诊断工具与治疗靶点的潜力,尤其在改善免疫治疗疗效方面展现出重要价值。本研究对该领域进行了全面综述,为学界提供了关于当前研究现状与未来发展方向的宝贵见解,并为个性化医疗与多学科协作领域的后续探索奠定了坚实基础。




