bulk mRNA-seq of Inpp5e mutant embryonic cortex against wild-type controls. bulk mRNA-seq of Inpp5e mutant embryonic cortex against wild-type controls

Primary cilia act as antennas in cell-cell signalling and are crucial for nervous system development. We explored their role in the development of the murine cerebral cortex using mice mutant for the ciliary gene Inpp5e. We investigated the transcription profile of control and Inpp5e loss-of-function mutants in the E12.5 dorsal telencephalon.