Inhibition of human placenta alkaline phosphatase (HPAP), bovine kidney tissue non-specific alkaline phosphatase (TNAP) and sirtuin 1 (SIRT1) by selected compounds.
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aSirtuin 1 inhibition was tested for N-methyllevamisole (7a) and suramin (5) as a positive control. b No inhibition was observed at ligand concentrations up to 10 mM. All assays were performed at least twice in duplicate. ND = not determined.
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2015-12-02
