SNPs with the lowest p-values in each cluster of SNPs reaching genome-wide significance (p−8).
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Positions refer to NCBI build 36. Alleles refer to coded/noncoded. CAF refers to the coded allele frequency in the pooled samples. Neff refers to the effective sample size in the meta-analysis, defined as N×R2, and reflects the loss of power with poor imputation compared to the total sample size shown in the first row. Beta coefficients per coded allele and p-values are given per cohort and for the meta-analysis. Genomic control has been applied in all samples. For heterogeneity, Q refers to the p-value from Cochran's Q test and I2 refers to the I2 statistic. All five SNPs are intronic.
创建时间:
2015-12-02



