Crystal Structure of Y188C Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X.
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Crystal Structure of Y188C Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X. Descriptor: ISOPROPYL (2S)-2-ETHYL-7-FLUORO-3-OXO-3,4-DIHYDROQUINOXALINE-1(2H)-CARBOXYLATE, PHOSPHATE ION, Reverse transcriptase/ribonuclease H, ... Authors: Ren, J, Nichols, C.E, Chamberlain, P.P, Weaver, K.L, Short, S.A, Chan, J.H, Kleim, J, Stammers, D.K. Deposit date: 2007-01-30 Release date: 2007-05-22 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Relationship of Potency and Resilience to Drug Resistant Mutations for GW420867X Revealed by Crystal Structures of Inhibitor Complexes for Wild-Type, Leu100Ile, Lys101Glu, and Tyr188Cys Mutant HIV-1 Reverse Transcriptases. J.Med.Chem., 50, 2007
创建时间：
2007-01-30
