Binding of OxP-11D and D-4F to oxidized and nonoxidized (phospho)lipids and sterols.

The mean KD values for apoA-I and D-4F are from [42], and those for OxP-11D are from this study. The ratio (KDD-4F)/(KDOxP-11D) is also shown. Ratios below 1 indicate that D-4F binds the lipid with higher affinity (lower KD) than OxP-11D. Ratios greater than 1 indicate that OxP-11D binds the lipid with higher affinity than D-4F. Abbreviations: PGPC-1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphorylcholine; POVPC-1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine; PEIPC-1-palmitoyl-2-(5,6-epoxyisoprostane E2)-sn-glycero-3-phosphorylcholine; KOdiA-PC-1-palmitoyl-2-(5-keto-6-octene-dioyl)-sn-glycero-phosphatidylcholine; HPETE-hydroperoxyeicosatetraenoic acid; HPODE-hydroperoxyoctadecadienoic acid, HETE- hydroxyeicosatetraenoic acid; HODE- hydroxyoctadecadienoic acid.