TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation

NIAID Data Ecosystem2026-03-11 收录

纤维化成纤维细胞激活

Yap信号通路

数据链接：

https://zenodo.org/record/3686073 数据链接链接失效反馈

官方服务：

资源简介：

The supplemental data for manuscript titled 'TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation'.

创建时间：

2020-02-26

Differential Gene expression in the mouse mammary tumors of PyMT-Malat1 wild-type (WT), PyMT-Malat1 knockout (KO) and PyMT-Malat1 knockout with Malat1 transgene expression (TG)

差异基因表达分析

Yap信号通路

Previously, lncRNA Malat1 knockout mice were generated by insertional inactivation. By crossing this line to MMTV-PyMT mammary tumor mouse model, we produced PyMT;Malat1 wild-type (WT) and PyMT;Malat1

NIAID Data Ecosystem40

Transcriptional effects of YAP/TAZ knockdown in fibroblasts. Transcriptional effects of YAP/TAZ knockdown in fibroblasts

成纤维细胞衰老

Yap信号通路

Gene expression profiles of the cells composing the dorsal skin of young control and YAP/TAZ knockout mice with the skin of a old mouse. Overall design: Single cell profiles were derived from the dors

NIAID Data Ecosystem40

YAP/TAZ inhibition induces metabolic and signaling rewiring resulting in new targetable vulnerabilities in NF2-deficient tumor cells

NF2缺陷肿瘤代谢

Yap信号通路

The NF2 gene, which encodes the Merlin protein, is a bona fide tumor suppressor whose mutations underlie inherited tumor syndrome Neurofibromatosis Type 2 (NF2). Recent large-scale genome sequencing s

NIAID Data Ecosystem30

MED12 dictates epithelial ovarian cancer cell ferroptosis sensi-tivity via YAP-TEAD1 signaling

卵巢癌铁死亡机制

Yap信号通路

Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy, with chem-otherapy resistance representing a major therapeutic challenge. Emerging evidence suggests that ferroptosis, an iro

NIAID Data Ecosystem40

DOCK1 siGENOME MDA-MB-231, low YAP:TAZ ratio (2).bmp

基因功能研究

Yap信号通路

DOCK1 siGENOME MDA-MB-231, hit for low YAP/TAZ ratio

NIAID Data Ecosystem30