Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions

Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions Descriptor: E3 ubiquitin-protein ligase Mdm2, Stapled peptide GAR300-Gm Authors: Groves, R.M, Ali, M.A, Atmaj, J, van Oosterwijk, N, Domling, A, Rivera, G.D, Ricardo, G.M. Deposit date: 2019-10-08 Release date: 2020-01-29 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions. Angew.Chem.Int.Ed.Engl., 59, 2020多组分肽钉合（Multicomponent Peptide Stapling）作为以多样性为导向的蛋白质-蛋白质相互作用抑制剂开发工具 描述对象：E3泛素蛋白连接酶Mdm2（E3 ubiquitin-protein ligase Mdm2） 钉合肽：GAR300-Gm 作者：Groves R.M.、Ali M.A.、Atmaj J.、van Oosterwijk N.、Domling A.、Rivera G.D.、Ricardo G.M. 提交日期：2019-10-08 发布日期：2020-01-29 最后修改日期：2024-01-24 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.4埃 引用文献：《多组分肽钉合作为蛋白质-蛋白质相互作用抑制剂开发的多样性导向工具》，《德国应用化学（Angew.Chem.Int.Ed.Engl.）》，第59卷，2020年