Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML. Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML
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下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA682420
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资源简介：
We report that loss of EZH2 provides leukaemia cells with a selective growth advantage, which mediates chemotherapy resistance. This resistance is conferred by up regulation of direct and indirect EZH2 target genes. Overall design: Description of expression changes due to EZH2 knockout in K562 cells.
创建时间：
2020-12-03
