Demographic and clinical data of the patients with MS/CIS and SC.

Table 2 shows the demographics and clinical data of the patient cohort. These demographic and clinical data are essentially as previously presented [18].aRefers to the patients included.bAge (in years) refers to age at the time of sampling.cMean number of attacks: mean number of attacks before the sampling time point.dDisease duration (in months): the period of time from debut of first symptom(s) to the sampling time point.eTime since last attack: the period of time (in days) from latest attack to the sampling time point.Mean total number of MRI white matter lesions were registered by fluid-attenuated inversion recovery (FLAIR) sequences on MRI. Abbreviations: RRMS (relapsing-remitting MS), PPMS (primary-progressive MS), CIS (clinically isolated syndrome), SC (symptomatic controls), N/A (not applicable or available), n (number of persons), EDSS (Expanded Disability Status Scale), CSF (cerebrospinal fluid).Demographic and clinical data of the patients with MS/CIS and SC.