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A structural role for histone methyltransferase MET-2 represses transcription independent of H3K9me catalysis

NIAID Data Ecosystem2026-03-13 收录

组蛋白甲基转移酶功能

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数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE168925 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2022-03-09

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DNA-蛋白质复合物

TRANSCRIPTIONAL REPRESSOR COPG/DNA COMPLEX Descriptor: DNA (5'-D(*CP*CP*CP*GP*TP*GP*CP*AP*CP*TP*CP*AP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*GP*AP*TP*TP*GP*CP*AP*TP*TP*GP*AP*GP*TP*GP*CP*AP*CP*GP*G)-3'),

Protein Data Bank Japan2023-12-27 更新30

Role of BEND3 in transcription repression

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ChIP-seq分析

We have uncovered that BEND3 is a heterochromatin-associated protein that functions as a transcription repressor. Expression of BEND3 correlates with the state of pluripotency, with a significant decl

NIAID Data Ecosystem30

KRAB–Zinc Finger Proteins and KAP1 Can Mediate Long-Range Transcriptional Repression through Heterochromatin Spreading

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异染色质扩散

Krüppel-associated box domain-zinc finger proteins (KRAB–ZFPs) are tetrapod-specific transcriptional repressors encoded in the hundreds by the human genome. In order to explore their as yet ill-define

NIAID Data Ecosystem20

Cohesin is involved in transcriptional repression of invasion-related genes

疟原虫基因调控

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The most virulent human malaria parasite, Plasmodium falciparum, has a complex life cycle between its human host and mosquito vector. Each stage of the cycle is driven by a specific transcriptional pr

NIAID Data Ecosystem30

ARv7 represses tumor suppressors genes in castration-resistant prostate cancer [RNA-Seq]

去势抵抗性前列腺癌

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Endocrine therapies in prostate cancer (PCa) treatment block androgen receptor (AR) function, but are palliative as tumors progress to a lethal, castration-resistant state (CRPC). CRPC remains depende

NIAID Data Ecosystem20

A structural role for histone methyltransferase MET-2 represses transcription independent of H3K9me catalysis

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