MLE, SE from a parabolic approximation around the minimum of the likelihood function, and ΔCI_LP from the actual likelihood profile in the standard σ range for the identifiable parameters of the two path model TP4 with relation to biological parameters, superscript m,f indicates sex-depen

alog-transformed. MLE, SE from a parabolic approximation around the minimum of the likelihood function, and ΔCILP from the actual likelihood profile in the standard σ range for the identifiable parameters of the two path model TP4 with relation to biological parameters, superscript m,f indicates sex-dependence, radiation-response parameters rI and rmCIN on dose D are given for an exposure duration of 1 week, rate λCIN(b) of destabilizing events in CIN increases exponentially with birth year b = 1945.6–e (age at exposure).