Long read epigenetics using a T2T genome
收藏NIAID Data Ecosystem2026-03-12 收录
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Using long read nanoNOMe data, we examined the methylation and chromatin accessibility patterns in satellite DNA, examining organized patterns of methylation along individual molecules. When exploring the alpha satellite higher order repeat (HOR) arrays in HG002, we discovered a distinctive region of hypomethylation and decreased chromatin accessibility consistent with CENPA associated HOR arrays.
创建时间：
2021-04-27
