HSF1 activates ANXA11-mediated glutamine metabolism by super enhancer long non-coding RNA LINC00857 in colorectal cancer [array]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE198224
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资源简介：
We shed light on a closely cooperative machinery between HSF1 and super enhancer for the first time in CRC. HSF1 could stimulate super enhancer activity by the enrichment of acetyltransferase P300 to LINC00857 promoter region, contributing to LINC00857 transcription. After knocking down HSF1 via 2 specific siRNA, total lncRNA expression profiles was acquired. HCT116 cell was used to acquire expression profiles of a total of 60495 lncRNA after HSF1 knockdown.
创建时间：
2022-08-31
