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Epithelium-only cultured stem cells isolated from human pluripotent stem cell derived intestinal organoids grown in matrigel and alginate

ChEBI2019-06-27 更新2026-07-12 收录

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上皮干细胞

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-7000 数据链接链接失效反馈

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Epithelium-only cultured stem cells isolated from human pluripotent stem cell derived intestinal organoids grown in matrigel and alginate

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创建时间：

2019-06-27

结肠炎炎症表型转录组

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We report the results of RNA-Seq on iPSCs, Definitive Endoderm (DE), Spheroids (Sph), and induced human intestinal organoids (iHIOs) from colitic and normal primary patient colon tissues Transcriptome

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Analysis of the transcriptomic changes in murine small and large intestinal organoids after the sudden expression of BRAFV600E and/or p53R172H. Analysis of the transcriptomic changes in murine small and large intestinal organoids after the sudden expression of BRAFV600E and/or p53R172H

癌基因转录组学

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BRAFV600E confers poor prognosis and a distinct molecular type of colorectal cancer, which is often associated with TP53 alterations. In order to understand how BRAFV600E and p53R172H promote tumorige

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Low-input, deterministic profiling of single-cell transcriptomes reveals individual intestinal organoid subtypes comprised of single, dominant cell types [organoids]

单细胞转录组学

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High-throughput single-cell RNA-sequencing (scRNA-seq) has transformed our ability to resolve cellular properties across systems. A key scRNA-seq catalyzer was the introduction of microdroplet-based s

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HNF4a acts as upstream functional regulator of intestinal Wnt3 and Paneth cell fate [RNA-seq]

肠道类器官

细胞分化调控

Maturation of Paneth cells depends on canonical Wnt signaling, but few transcriptional regulators have been identified to this end. We showed that HNF4a plays a non-redundant and crucial role in suppo

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4week organoid VS 54week organoid. Mus musculus

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年龄相关转录组

Transcriptional profiling of mouse intestinal organoids comparing 4 week mouse with 54 week mouse Overall design: Two-condition experiment, 4 week intestinal organoids vs. 54 week intestinal organoids

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Epithelium-only cultured stem cells isolated from human pluripotent stem cell derived intestinal organoids grown in matrigel and alginate

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