Reduced inflammatory lesion by transplantation of rfNSCs-IDO.
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The EAE model exhibited the abnormal infiltration of lymphocytes into the brain. (A) Migration of rfNSCs to the cerebral cortex was confirmed by immunofluorescent staining. SN12C-GFP was used as a positive control. Scale bars, 50 μm. (B) Abnormal infiltration of lymphocytes into the cerebral cortex was observed in the HBSS control group, whereas the rfNSCs-Cont and rfNSCs-IDO groups showed less or no lymphocyte infiltration. Blue arrowheads indicated the magnified region of each group. Scale bars, 100 μm. (C) The infiltration of CD25+ activated T lymphocyte in the cerebral cortex was visualized by immunofluorescent staining. Red arrowheads indicate the magnified region of each group. Scale bars, 100 μm. (D) The thickness of the lymphocyte layer was measured at the cerebral cortex among the experimental groups. (n = 6, * p p
创建时间：
2016-02-23
