Crystal structure of P.aeruginosa LpxC in complex with inhibitor
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Crystal structure of P.aeruginosa LpxC in complex with inhibitor Descriptor: (2R)-2-azanyl-4-methylsulfonyl-N-[3-(trifluoromethyloxy)phenyl]butanamide, CHLORIDE ION, MAGNESIUM ION, ... Authors: Mima, M, Baker, L.M, Surgenor, A, Robertson, A. Deposit date: 2020-07-07 Release date: 2020-12-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity. J.Med.Chem., 63, 2020
铜绿假单胞菌(Pseudomonas aeruginosa)LpxC与抑制剂(2R)-2-氨基-4-甲磺酰基-N-[3-(三氟甲氧基)苯基]丁酰胺、氯离子、镁离子等形成复合物的晶体结构 描述:(2R)-2-氨基-4-甲磺酰基-N-[3-(三氟甲氧基)苯基]丁酰胺、氯离子、镁离子…… 作者:Mima M、Baker L.M、Surgenor A、Robertson A 存放日期:2020-07-07 发布日期:2020-12-02 最后修改日期:2023-11-29 实验方法:X射线衍射(分辨率2 Å) 引用:《基于片段发现具有抗菌活性的新型非羟肟酸类LpxC抑制剂》,J.Med.Chem., 63, 2020



