Crystal structure of Celecoxib bound to S121P murine COX-2 mutant
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Crystal structure of Celecoxib bound to S121P murine COX-2 mutant Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE, ... Authors: Malkowski, M.G, Orlando, B.J. Deposit date: 2016-05-11 Release date: 2016-10-26 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.822 Å) Cite: Fatty Acid Binding to the Allosteric Subunit of Cyclooxygenase-2 Relieves a Tonic Inhibition of the Catalytic Subunit. J.Biol.Chem., 291, 2016
创建时间:
2016-05-11



