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Granzyme K+ CD8 T cells form a core population in inflamed human tissue

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NIAID Data Ecosystem2026-05-02 收录
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Using data from the AMP RA Immune Repertoire Profiling dataset, synovial tissue and synovial fluid CD8+ T cells were found to be predominated by a population of effector CD8+ T cells characterized by high expression of granzyme K and low expression of granzyme B and perforin as described in Science Translational Medicine https://doi.org/10.1126/scitranslmed.abo0686.

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2025-09-04
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