IPA summary for 3DR±UV vs. 3DC±UV, (>2fold, p<0.05).

aIPA analysis returned several categories of known networks, molecular and cellular functions, and upstream regulators that could be considered important differences between radical polymerization and conjugate addition. This table summarizes the specific changes between these two polymerization groups at each level of evaluation (whole network activity, group function, specific protein activation) and gives the relative strengths of these components in the relevant statistical measure.bIPA network score: For networks, the IPA network score is a relative measure of relevance, with the two highest scores reported.cp-value range (# molecules): For molecular and cellular functions, each function, such as “Cellular Development”, represents a combination of lower level functions, each with a p-value. Thus the significance of these higher level functions is given as a range that covers the p-values of the lower level functions. The # molecules is the number of user input dataset molecules associated with that higher level function.dp-value (activation z-score, prediction): For individual upstream regulators, the expected cascade of transcriptional changes in downstream molecules is evaluated to determine if a particular upstream regulator is acting, and directions and magnitudes of particular changes can be used to determine the activation z-score. Positive z-scores above 2 predict activation while negative z-scores below -2 predict inhibition.IPA summary for 3DR±UV vs. 3DC±UV, (>2fold, p