Poly (ADP-ribose) polymerase 1 (PARP-1) is a critical enzyme involved in DNA damage repair and recombination, and shows great potential for drug development in the treatment of cancers with defective
ABSTRACT The aims of this study were to synthesize a series of thiosemicarbazones and their thiazole derivatives, to investigate their cytotoxic activity against three human cancers and normal (Vero c
Two new abietane diterpenoids (1 and 2) and two known analogs (3 and 4) were isolated from the whole plants of Phlegmariurus carinatus. Their structures were determined by comprehensive spectroscopic
In this study, α-aminophosphonates and oxazaphosphinanes were synthesized and evaluated for their potential anticancer activity. The objective was to assess their cytotoxic effects against various can
