Additional file 7: of YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias

YKL-40 positive astrocytes associated to β-amyloid plaques. Confocal Z-stack images obtained from double-labelling staining with YKL-40 (green) and β-amyloid (red) antibodies in the hippocampus of AD tissue. Z-stacks from representative senile β-amyloid plaque (A) and diffuse amyloid plaque (B) is shown. DRAQ5 staining is shown in blue. Individual channels as well as merge images are shown. Distance between-Z Stacks sections = 0.5 μm. (ZIP 2287 kb)