The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site and L-Tryptophan at the enzyme beta-site

The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site and L-Tryptophan at the enzyme beta-site Descriptor: 1,2-ETHANEDIOL, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, CESIUM ION, ... Authors: Hilario, E, Dunn, M.F, Mueller, L.J. Deposit date: 2020-07-29 Release date: 2021-08-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site and L-Tryptophan at the enzyme beta-site. To be Published

鼠伤寒沙门氏菌（Salmonella typhimurium）色氨酸合酶突变体β-S377A的内部醛亚胺晶体结构，该复合物结合了α位点的抑制剂2-({[4-(三氟甲氧基)苯基]磺酰基}氨基)乙基二氢磷酸酯（F9F）、金属配位位点的铯离子，以及酶β位点的L-色氨酸。描述符：1,2-乙二醇、2-({[4-(三氟甲氧基)苯基]磺酰基}氨基)乙基二氢磷酸酯、铯离子……作者：Hilario, E、Dunn, M.F、Mueller, L.J。提交日期：2020-07-29；发布日期：2021-08-04；最后修改日期：2023-10-18。实验方法：X射线衍射（1.55埃）。引用信息：鼠伤寒沙门氏菌色氨酸合酶突变体β-S377A的内部醛亚胺晶体结构，该复合物结合α位点的抑制剂2-({[4-(三氟甲氧基)苯基]磺酰基}氨基)乙基二氢磷酸酯（F9F）、金属配位位点的铯离子与酶β位点的L-色氨酸。待发表