Discovery of a degrader for AML differentiation therapy

Name: Discovery of a degrader for AML differentiation therapy
Creator: Tsinghua University, school of pharmaceutical sciences
Published: 2020-09-21T16:25:45+08:00

integrated proteome resources2026-02-07 收录

AML治疗

靶向蛋白质降解药物

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资源简介：

Discovery of a degrader for AML differentiation therapy

提供机构：

Tsinghua University, school of pharmaceutical sciences

创建时间：

2020-09-21

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PARP抑制剂机制

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EGFR突变肺癌治疗

Drug resistance caused by epidermal growth factor receptor (EGFR) mutation has largely limited the clinical use of EGFR tyrosine kinase inhibitors (EGFR-TKIs) for the treatment of non-small-cell lung

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Discovery of a dual PROTAC for degrading WDR5 and Ikaros oncoproteins as therapeutics. Discovery of a dual PROTAC for degrading WDR5 and Ikaros oncoproteins as therapeutics

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癌症治疗机制

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

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Expression data of AML cells treated with out without H4. Expression data of AML cells treated with out without H4

AML治疗

基因表达谱分析

Safer and more efficient therapy for patients with acute myeloid leukemia (AML) is needed and differentiation therapy is an appealing option to eradicate leukemic stem cells blocked in differentiation

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Discovery of a degrader for AML differentiation therapy

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