The MPP list in S1 Table was truncated by removing the 15 highly charged proteins (8 anionic ones with charge + 5%), and the truncated list is presented together with the UPP list from S2 Table. Only
‘Group 2’ amino acids, as defined in the main text, are shown in italics on the diagonal – all three exhibited an increase in charge of +1 in 1985, followed by a reversion before 2000. All other amino
