Demographic characteristics and spontaneous production of macrophage derived chemokines of patients with or without acute exacerbation.

Definition of abbreviations: AE: patients with an acute exacerbation at baseline; FVC: forced vital capacity; DLco: diffusing lung capacity for carbon monoxide, CPI: composite physiologic index, AM: alveolar macrophage; LYM: lymphocyte; PMN: polymorphonuclear neutrophils; EOS: eosinophils; n.s.: not significant. Data are expressed as mean ± standard deviation. *p value < 0.05 and †p value < 0.0001 for comparison of controls and all patients with IPF; p values comparing IPF patients w/o AE are listed in the last column. ‡Not feasible for all patients. Demographic characteristics and spontaneous production of macrophage derived chemokines of patients with or without acute exacerbation.