piRNA expression profiling for 6 human samples

To further define the role of piRNAs in the development of renal cancer, we employed piRNA microarray expression profiling as a discovery platform to identify differentially expressed piRNAs. Radical nephrectomy was performed on 3 patients with renal cancer, and the postoperative pathology was clear cell renal cell carcinoma. The cancer tissues and adjacent normal tissues of the patients were taken for piRNA sequencing. And the differentially high-expressed and differentially low-expressed piRNAs were analyzed by bioinformatics. Radical nephrectomy was performed on 3 patients with clear cell renal cell carcinoma, and the expression of piRNA in renal cancer tissue and adjacent tissue was measured.