ATAC-sequencing to evaluate the global chromatin dynamics in the absence of hepatic-HMGB1 in livers from mice on fed with chow diet or after a metabolic stress induced by a fasting (6hours)-refeeding (8hours) challenge.. ATAC-sequencing to evaluate the global chromatin dynamics in the absence of hepatic-HMGB1 in livers from mice on fed with chow diet or after a metabolic stress induced by a fasting (6hours)-refeeding (8hours) challenge.

Hepatocyte nuclei were purified from liver samples harvested from HMGB1fl/fl (n=2) and HMGB1ΔHep (n=2) mice upon chow diet feeding or after fasting-refeeding.