A new chromone derivative from an endophytic <i>Aspergillus</i> sp. GXNU-B1
收藏数据链接：
官方服务：
资源简介：
A new chromone derivative, aspergione A (<b>1</b>), along with seven known metabolites, was isolated from a mangrove endophytic fungus, <i>Aspergillus</i> sp. GXNU-B1, which was collected from mangrove <i>Acanthus ilicifolius</i> L. Their structures and the absolute configuration of <b>1</b> were elucidated based on the analysis of HR-ESI-MS, NMR, and ECD calculation. Compounds <b>1</b>-<b>8</b> were evaluated for their anti-inflammatory effects on the production of nitricoxide (NO). Compounds <b>1</b> and <b>8</b> have potent inhibitory effects against NO production in activated macrophages with IC<sub>50</sub> values of 38.26 and 44.30 <i>μ</i>M, respectively.
提供机构：
Taylor & Francis创建时间：
2023-02-23
