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A multispecific antibody confers pan-reactive SARS-CoV-2 neutralization and prevents immune escape

NCATS Open Data2022-08-05 更新2026-08-08 收录

广谱中和抗体

免疫逃逸预防

数据链接：

https://doi.org/10.1101/2022.07.29.502029 数据链接链接失效反馈

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资源简介：

A multispecific antibody confers pan-reactive SARS-CoV-2 neutralization and prevents immune escape

应用场景：

创建时间：

2022-08-04

抑制剂评估

广谱中和抗体

Inhibitory activity of IBP-CP24 (C34 as a control) or bNAbs (NBD556 as a control) when used alone or in combination against infection HIV-1 IIIB or JR-CSFa.

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Identification of Non-HIV Immunogens That Bind to Germline b12 Predecessors and Prime for Elicitation of Cross-clade Neutralizing HIV-1 Antibodies

HIV疫苗免疫原设计

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A fundamental challenge for developing an effective and safe HIV-1 vaccine is to identify vaccine immunogens that can initiate and maintain immune responses leading to elicitation of broadly neutraliz

Figshare2016-01-15 更新40

A three component mix of thioredoxin-L2 antigens elicits broadly neutralizing responses against oncogenic human papillomaviruses.

HPV疫苗研发

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The epitope sequence was provided in Rubio et al. Vaccine 2009 27:1949 [PMID 19368776]. The L2 pseudovirion-based neutralization assay (L2-PBNA) was used to determine immunogenicity and cross-reactivi

ImmuneData10

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-34

冠状病毒结构

广谱中和抗体

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-34 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-

Protein Data Bank Japan2024-10-23 更新40

Chothia numbered VH sequences of isolated antibodies and published VH1-69 derived bNAbs.

抗体序列分析

广谱中和抗体

Chothia numbered VH sequences of isolated antibodies and published VH1-69 derived bNAbs.

NIAID Data Ecosystem20