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Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues

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In an effort to define transcriptional heterogeneity in the stromal cell compartment of lymph nodes scRNA-seq analysis of CD45- cells from skin-draining LNs (SLN) was performed. Flow sorted CD45 depleted single cell suspension from SLN of ten mice were profiled by 10x 3' single-cell RNA-sequencing in two runs, each containing cells from five mice.

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