BETA-N-ACETYLHEXOSAMINIDASE MUTANT E540D COMPLEXED WITH DI-N ACETYL-D-GLUCOSAMINE (CHITOBIASE)

BETA-N-ACETYLHEXOSAMINIDASE MUTANT E540D COMPLEXED WITH DI-N ACETYL-D-GLUCOSAMINE (CHITOBIASE) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-N-ACETYLHEXOSAMINIDASE, SULFATE ION Authors: Prag, G, Papanikolau, Y, Tavlas, G, Vorgias, C.E, Petratos, K, Oppenheim, A.B. Deposit date: 2000-03-17 Release date: 2000-09-20 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structures of chitobiase mutants complexed with the substrate Di-N-acetyl-d-glucosamine: the catalytic role of the conserved acidic pair, aspartate 539 and glutamate 540. J.Mol.Biol., 300, 2000β-N-乙酰己糖胺酶（beta-N-acetylhexosaminidase）突变体E540D与二-N-乙酰-D-葡萄糖胺（di-N-acetyl-D-glucosamine，几丁二糖酶chitobiase）复合物 描述项：2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖、β-N-乙酰己糖胺酶、硫酸根离子 作者：Prag G、Papanikolau Y、Tavlas G、Vorgias C.E.、Petratos K、Oppenheim A.B. 提交日期：2000-03-17 发布日期：2000-09-20 最后修改日期：2024-11-06 实验方法：X射线衍射（分辨率1.9 Å） 引用文献：结合底物二-N-乙酰-D-葡萄糖胺的几丁二糖酶突变体结构：保守酸性对天冬氨酸539与谷氨酸540的催化作用。《分子生物学杂志》，300卷，2000年