Prepulse inhibition of the startle response and radioligand binding assays

Dataset 1. PPI data.The percent PPI data is provided for each prepulse decibel level tested. This raw behavioral data reflects the percentage of inhibition in prepulse-pulse trials compared with pulse-only trials for each prepulse intensity tested. The data is graphically presented in Figure 2.
Dataset 2. Regional radioligand binding data.The radioligand binding data presented in Figures 3 – 7 is provided in fmol/mg tissue equivalent. In a few instances, tissue damage during processing prevented reliable densitometry within a region. These data were omitted from the study (indicated by blank cells in the spreadsheet). Additionally, we were unable to block nonspecific binding in all tissue samples from rat O0 for either radioligand, possibly due to tissue damage that was isolated to this case, so this data were omitted as well. AC = anterior cingulate, IC = insular cortex.

数据集1：PPI 数据集。本数据集提供了每个测试的预脉冲分贝水平的 PPI 百分比数据。该原始行为数据反映了与脉冲单独试验相比，在测试的每个预脉冲强度下的预脉冲-脉冲试验中抑制的百分比。这些数据以图形形式呈现于图2中。
数据集2：区域放射性配体结合数据。图3至图7中展示的放射性配体结合数据以 fmol/mg 组织当量提供。在少数情况下，处理过程中组织损伤阻止了该区域内可靠的光密度测定。这些数据被排除在研究之外（在电子表格中以空白单元格表示）。此外，由于可能仅限于本例的组织损伤，我们无法阻断来自大鼠 O0 的所有组织样本中两种放射性配体的非特异性结合，因此这些数据也被排除在外。AC = 前扣带回，IC = 岛叶皮层。