Association of Multiparametric MRI Quantitative Imaging Features with Prostate Cancer Gene Expression in MRI-targeted Prostate Biopsies. Homo sapiens
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA324676
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资源简介：
Standard clinicopathological variables are inadequate for optimal management of prostate cancer patients. While genomic classifiers have improved patient risk classification, the multifocality and heterogeneity of prostate cancer can confound pre-treatment assessment. The objective is to investigate the association of multiparametric (mp)MRI quantitative features with prostate cancer risk gene expression profiles in mpMRI-guided biopsies tissues. Overall design: Global gene expression profiles were generated from 17 mpMRI-directed diagnostic prostate biopsies using an Affymetrix platform. Spatially distinct imaging areas (‘habitats’) were targeted following MRI/3D-Ultrasound fusion. Radiomic features were extracted from biopsy regions and normal appearing tissues
创建时间：
2016-04-26
