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EZH2 is a potential therapeutic target for H3K27M mutant paediatric gliomas. EZH2 is a potential therapeutic target for H3K27M mutant paediatric gliomas

NIAID Data Ecosystem2026-03-09 收录

胶质瘤靶向治疗

EZH2抑制研究

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA338311 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2016-08-09

胶质瘤靶向治疗

铜死亡机制研究

Additional file 13.

DataCite Commons2024-08-18 更新90

Supplementary Table 1 from The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells

m6ARNA修饰

胶质瘤靶向治疗

Supplementary Table

NIAID Data Ecosystem30

Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial 1 homeostasis and increases antitumor activity against glioblastoma

胶质瘤靶向治疗

线粒体功能与细胞稳态

Background: Few druggable targets have been discovered in glioblastoma (GBM); however, increasing knowledge has uncovered two hallmarks of this disease: epigenetic modifications and cell cycle dysregu

NIAID Data Ecosystem20

Identification and validation of GPD1 as an essential cancer stem cell specific target in glioblastoma (RNA-seq: Gpd1 KO). Identification and validation of GPD1 as an essential cancer stem cell specific target in glioblastoma (RNA-seq: Gpd1 KO)

胶质瘤靶向治疗

癌症干细胞休眠调控

Cancer stem cells (CSCs) are attractive targets for cancer therapy, however, little is known about how to target CSCs without affecting the normal stem cell population. Here we report the ribosome-pro

NIAID Data Ecosystem70

Evaluation of Tyrosine Kinase Inhibitor Combinations for Glioblastoma Therapy

胶质瘤靶向治疗

酪氨酸激酶抑制剂组合疗效

Glioblastoma multiforme (GBM) is the most common intracranial cancer but despite recent advances in therapy the overall survival remains about 20 months. Whole genome exon sequencing studies implicate

Figshare2016-01-19 更新20

EZH2 is a potential therapeutic target for H3K27M mutant paediatric gliomas. EZH2 is a potential therapeutic target for H3K27M mutant paediatric gliomas

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