Clinicopathologic details of breast cancer patients.

Summary of MMP13 expression and clinicopathologic characteristics of primary breast tumors.
Tissue samples were graded and MMP13 expression was determined by immunofluorescence, as described in Materials and Methods. All patients were diagnosed with invasive/infiltrating ductal carcinoma (IDC). The MMP13 immunofluorescence images of the samples from Patients 1 and 2 are shown in Figure 7. N/A = not available. The tumors from all the patients, except patient 7 where HER-2 status was not determined, were negative for HER-2. Estrogen receptor and progesterone receptor status was graded as − = negative, + = weak, ++ = intermediate and +++ = strong expression. MMP13 expression was determined as intra-tumor (T), stromal (S) and vasculature (V).