Mettl3 regulates late-stage retinogenesis
收藏Alliance of Genome Resources2026-08-01 收录
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To study the function of Mettl3 during retinal development, we used Six3-Cre and Mettl3floxed mice to conditionally knock out Mettl3 from retinal progenitor cells. The mutant mice show defects in late-stage retinogenesis and structural and physiological homeostasis of the retina. Retinas of postnatal day 7 Six3-Cre+; Mettl3floxed/floxed mice (4 samples), as well as retinas of their littermate control mice (4 samples), were collected into TRIZol, and processed for RNA-seq.
