This is a new method to reduce bias from PCR amplified libraries, here applied to the problem of detecting a small increase of reads on chromosome 21 in a mixture of normal DNA and trisomy 21 DNA.
Higher levels of aneuploidy, characterized by imbalanced chromosome numbers, are associated with lethal progression in prostate cancer. However, how aneuploidy contributes to prostate cancer aggressiv
The current imaging dataset (n=~4000) provides brightfield images of cultured primary human fibroblasts (in vitro) aged through the cellular lifespan. The dataset was generated using the Fisherbrand™