We undertook the identification of inhibitors of an enzyme of the Trypanosoma cruzi, the agent of Chagas' disease shown to be essential for its proliferation. The genome compares an original parasite
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-111 Descriptor: 5-[2-(4-methylphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE
