Histone acetylation, governed by histone deacetylase (HDAC) enzymes, plays a pivotal role in cell biology. Elevated HDAC expression is linked to a poor prognosis in various diseases, including cancer,
Values are means of four independent assays. The different compounds were used at concentration for which no direct antibacterial effect was observed. EDTA was used at 1 mM ; SDS at 100 µg/ml; Tx-100
Bacillus subtilis YjoB has been an uncharacterized AAA+ ATPase which consists of a single ATPase domain and a unique N-terminal domain. To understand the molecular function of YjoB, we identified YjoB