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The Sen1 Helicase Prevents Genome-Wide Spurious Transcription by Controlling Transcription Termination by RNAPII

Alliance of Genome Resources2026-08-01 收录

转录终止调控

RNA聚合酶转录

数据链接：

https://www.yeastgenome.org/dataset/GSE17559 数据链接链接失效反馈

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It is currently believed that termination by RNAPII occurs differently depending whether a transcript contains or lacks a polyadenylation signal (PAS)

应用场景：

蛋白质-肽段相互作用

RNA聚合酶转录

Solution structure of Rtt103 CTD-interacting domain bound to a Thr4 phosphorylated CTD peptide Descriptor: PRO-SER-TYR-SER-PRO-PTH-SER-PRO-SER-TYR-SER-PRO-THR-SER-PRO-SER, Regulator of Ty1 transpositi

Protein Data Bank Japan2024-11-20 更新40

Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA polymerase II CTD peptide phosphorylated at Ser-2, Ser-5 and Ser-7

蛋白质晶体

RNA聚合酶转录

Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA polymerase II CTD peptide phosphorylated at Ser-2, Ser-5 and Ser-7 Descriptor: Hexapeptide, PHOSPHATE ION, RNA poly

Protein Data Bank Japan2024-10-30 更新20

CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation.

转录终止调控

RNA加工

CDK9 is a kinase critical for the productive transcription of protein-coding genes by RNA polymerase II (pol II). As part of P-TEFb, CDK9 phosphorylates the carboxyl-terminal domain (CTD) of pol II an

NIAID Data Ecosystem20

Evidence for a mediator cycle at the initiation of transcription

转录调控

RNA聚合酶转录

Free and elongating (DNA-bound) forms of RNA polymerase II were separated from yeast. Most cellular polymerase II was found in the elongating fraction, which contained all enzyme phosphorylated on the

PubMed Central1997-06-10 更新30

ZSCAN5B and its primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression [SiRNA RNA-Seq data set]. Homo sapiens

RNA聚合酶转录

有丝分裂进程分析

Particularly in the context of differentiation and development, the importance of three-dimensional chromatin architecture to gene regulatory mechanisms is becoming increasingly clear. The most ancien

NIAID Data Ecosystem20

The Sen1 Helicase Prevents Genome-Wide Spurious Transcription by Controlling Transcription Termination by RNAPII

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