Population-based prospective studies for the association between diabetes and changes in cognitive performance.

*Logistic regression model revealed that baseline DM was a predictor of major cognitive decline, defined as a 9-point or greater decrease in scores on Modified MMSE, 4-point or greater decrease in scores on the word-list test. BDI indicates Beck Depression Inventory, BMI body mass index, CDR Clinical Dementia Rating, CES-D Center for Epidemiologic Studies Depression Scale, CHF chronic heart failure, CNS central nervous system, DSST Digit Symbol Substitution test, FG fasting glucose test, Hx self-report history of diabetes or a physician's diagnosis of diabetes, MMSE Mini-Mental Status Examination, Mx use of anti-diabetes medications including insulin, NFG non-fasting glucose test, OGTT oral glucose tolerance test, Rec diabetes mellitus ascertained from medical records, TIA transient ischemic attack, TICS Telephone Interview for Cognitive Status, WAIS Wechsler Adult Intelligence Scale.